ICAM-1: Isoforms and Phenotypes

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ICAM-1: isoforms and phenotypes.

ICAM-1 plays an important role in leukocyte trafficking, immunological synapse formation, and numerous cellular immune responses. Although considered a single glycoprotein, there are multiple membrane-bound and soluble ICAM-1 isoforms that arise from alternative splicing and proteolytic cleavage during inflammatory responses. The function and expression of these isoforms on various cell types a...

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The Effects of Resistance Training on VCAM-1, ICAM-1 and CRP in Diabetic Rats

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Mutation in collagen II alpha 1 isoforms delineates Stickler and Wagner syndrome phenotypes

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Single-molecule measurements of the interaction of leukocyte function-associated antigen-1 (LFA-1), expressed on Jurkat T cells, with intercellular adhesion molecules-1 and -2 (ICAM-1 and ICAM-2) were conducted using atomic force microscopy (AFM). The force spectra (i.e., unbinding force versus loading rate) of both the LFA-1/ICAM-1 and LFA-1/ICAM-2 interactions were acquired at a loading rate ...

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ژورنال

عنوان ژورنال: The Journal of Immunology

سال: 2014

ISSN: 0022-1767,1550-6606

DOI: 10.4049/jimmunol.1400135